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A recent study documented impaired production and abnormal ratios of porphyrins in children with autism.

Because porphyrin is involved in the production of functional heme/hemoglobin, and because this appears to be disordered in autism, the impaired delivery of oxygen to cells will be improved when HBOT bypasses hemoglobin-dependent oxygenation.

Children with autism have been shown to have increased oxidative stress and less reduced (active) glutathione HBOT, especially when using pressures less than 2.0 atmospheres, can up-regulate these antioxidant enzymes and afford antioxidant protection against oxidative stress.

Mitochondria are the energy producing organelles of the body.

This explanation is in keeping with the clinical results I see.

In my clinic improved bowel function is in the top 20 most commonly seen benefits.

Once inflammation is reduced the secondary vascular narrowing is improved allowing increasing amounts of red blood cells carrying oxygen to reach the hypoxic areas and SPECT scans will once again "light up" turning from blue to yellow.C-reactive protein and high levels of cytokines have been shown to decrease with HBOT.One study demonstrates that the anti-inflammatory effect from HBOT is probably due to pressure effects and not necessarily increased oxygen tension.Likewise it is my theory that it only takes a little bit of increased oxygen tension for viruses to leave.Studies have shown abnormities in the autistic brain whereby it does not produce and subsequently does not use serotonin properly.

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Then most parents will state what they are doing, e.g. Because dissolved oxygen is not confined to a hemoglobin molecule, it can go wherever "body water goes" and therefore reach 'deeper tissues' more easily and more consistently than ever before Because no test is able to predict which child may and which child may not respond to extra pressure and/or extra oxygen (in contrast to excessive oxygen), I let nature take its course and prescribe a clinical trial of HBOT for all my children Though I let "nature take its course", I would not consider prescribing or administering HBOT to children with autism unless there was good scientific evidence to support its use.